Adipocyte dedifferentiation
WebFeb 10, 2024 · During the dedifferentiation process, mature adipocytes lose lineage gene expression profile and acquire the typical MSCs immunophenotype and gene expression … WebMar 18, 2024 · Adipocytes derived from the differentiation of murine 3T3-F442A or 3T3-L1 cells, that are clonal sublines isolated from 3T3 mouse embryonic fibroblasts, undergo sequential phenotypic and functional alterations that differentiate them from the mature adipocytes from which they derive upon exposure to cancer cells or their conditioned …
Adipocyte dedifferentiation
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WebThis study suggests that promoting the dedifferentiation of mature adipocytes can improve the survival rate and quality of fat grafts. © The Author(s) 2024. Published by Oxford University Press on behalf of the Aesthetic Society. All rights reserved. WebJun 8, 2024 · Mature, adipocyte derived, dedifferentiated fat cells can differentiate into smooth muscle-like cells and contribute to bladder tissue regeneration. J. Urol. 182 , …
WebApr 22, 2015 · The dedifferentiation of adipocytes has been observed in many in vitro experiments; however, it remains unknown whether adipocytes dedifferentiate in vivo. … WebJun 5, 2024 · Dysfunction of adipocytes and adipose tissue is a primary defect in obesity and obesity-associated metabolic diseases. Interferon regulatory factor 3 (IRF3) has …
WebJun 1, 2011 · In these studies, adipocyte dedifferentiation was identified in cells that underwent the following steps: (1) morphological changes from lipid-loaded round cells into fibroblastic cells devoid of... WebBefore transformation, Ad/N1ICD adipocytes undergo dedifferentiation that leads to lipodystrophy and metabolic dysfunction. Although concomitant Pten deletion normalizes the glucose metabolism of Ad/N1ICD mice, it dramatically accelerates the …
WebSep 6, 2024 · Dedifferentiated adipocytes, by definition, acquire broader developmental potential, implying that they can be differentiated into other cells besides adipocytes. 6 …
WebJan 22, 2024 · The dedifferentiation ratio of adipocytes is found to be higher on a stiff substrate as compared to that on a soft substrate; this effect is further augmented by the … ガオホワイト 女優WebOct 9, 2024 · Adipocytes are a group of cells that respond to various stimuli and have high plasticity. It has been reported that mature dermal adipocytes undergo dedifferentiation and redifferentiation under different physiological and pathophysiological conditions [ 20 ]. カオマークWebRemarkably, the dedifferentiation of adipocytes only occurs when they were cultured in common cell growth medium (without adipogenic inducer), which indicates that some regulatory factors exist in the cell culture microenvironment that influences the process of cell dedifferentiation. がおまるWebApr 3, 2024 · The DEGs related to lipid metabolism were mainly involved in adipocyte differentiation (such as CEBPA, PPARG, RBP7, and RXRG ), fatty acid transport and fatty acid synthesis (such as ELOVL1, ELOVL6, FABP3, FABP4, FADS6, FADS1 L1, SCD, and SCD5 ), lipid stabilization (such as CIDEC, PLIN3, PLIN4, and MOGAT1 ), and lipolysis … patel devonWebJun 5, 2024 · Dysfunction of adipocytes and adipose tissue is a primary defect in obesity and obesity-associated metabolic diseases. Interferon regulatory factor 3 (IRF3) has been implicated in adipogenesis.... patel devenWebJun 1, 2011 · In these studies, adipocyte dedifferentiation was identified in cells that underwent the following steps: (1) morphological changes from lipid-loaded round cells … patel deveshWebOct 10, 2024 · Recently, dedifferentiation, whereby a mature adipocyte is reverted to an undifferentiated progenitor-like status, has been reported as a mechanism underlying … patel dev