WebMATERIAL SAFETY DATA SHEET _____ Material Name: Cisplatin Solution for Injection - 0.5 and 1 mg/ml Revision date: 02-Jan-2007 Page 2 of 7 Version: 1.1 EU Hazard Symbols: EU Risk Phrases: R45 - May cause cancer. R46 - May cause heritable genetic damage. Note: This document has been prepared in accordance with standards for workplace … WebMaterial Name: Cisplatin Injection Sodium chloride Molecular Formula: Rat Oral LD50 3000 mg/kg Mixture Mouse Oral LD50 4000 mg/kg Version: 1.0 Cisplatin Mannitol Molecular Weight: Rat Oral LD 50 13500 mg/kg Mixture Rat Oral LD 50 25.8 mg/kg Mouse Oral LD 50 22 g/kg Page 5 of 9
A Systematic Review of Strategies to Prevent Cisplatin …
WebMar 1, 2024 · Postoperative chemoradiotherapy with 3-weekly cisplatin at 100 mg/m 2 is standard treatment for patients with high-risk factors for recurrence. 2 - 4 However, the 3-weekly dosage has raised concerns about insufficient cisplatin delivery because of high-dose–related toxicity, 2, 3, 5 and chemoradiotherapy with weekly cisplatin is widely … http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_handout.pdf tretinoin microsphere gel buy
Survival and Toxicity After Cisplatin Plus ... - JCO …
WebSep 1, 2024 · Cisplatin for injection is a cytotoxic drug. Follow applicable special handling and disposable procedures. 1 Reconstitution Reconstitute 50 mg vials with 50 mL of … WebJun 1, 2024 · months with gemcitabine and cisplatin versus 8.1 months with gemcitabine monotherapy.7 Outcomes in the gemcita-bine and cisplatin group of TOPAZ-1 were comparable to historical controls of gemcitabine and cisplatin,7,22 with a median overall survival of 11.5 months and estimated 18-and 24-month survival rates of 25.6% and … WebJul 3, 2024 · Cisplatin is a widely used chemotherapeutic agent with a high degree of ototoxicity and an average incidence of over 60% ( Karasawa and Steyger, 2015 ). Ototoxicity depends on several factors, including patient age, cumulative dose of cisplatin, and genetic susceptibility ( Landier, 2016; Lanvers-Kaminsky and Ciarimboli, 2024 ). tretinoin mix with moisturizer