WebThe lipase is expressed as different isoforms produced from tissue-specific alternative promoters. All isoforms are composed of an N-terminal domain and a C-terminal … Web4 apr. 2024 · Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 6 and hypertension. Orthologous to human LIPE (lipase E, hormone sensitive type). [provided by Alliance of Genome Resources, Apr 2024] Other designations. hormone-sensitive lipase, lipase, hormone sensitive, monoacylglycerol lipase LIPE, retinyl ester …
Adipocyte hormone-sensitive lipase: a major regulator of lipid ...
Hormone-sensitive lipase (EC 3.1.1.79, HSL), also previously known as cholesteryl ester hydrolase (CEH), sometimes referred to as triacylglycerol lipase, is an enzyme that, in humans, is encoded by the LIPE gene, and catalyzes the following reaction: (1) diacylglycerol + H2O = monoacylglycerol + a carboxylate … Meer weergeven During fasting-state the increased free fatty acid secretion by adipocyte cells was attributed to the hormone epinephrine, hence the name "hormone-sensitive lipase". Other catecholamines and Meer weergeven Extracellular hormones, such as glucagon, epinephrine, Thyroid-Stimulating Hormone, or ACTH, bind to their respective G protein–coupled receptors (GPCR). When a GPCR is activated by its extracellular ligand, a conformational change is induced in the … Meer weergeven • Hormone-Sensitive+Lipase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Meer weergeven The main function of hormone-sensitive lipase is to mobilize stored fats. HSL functions to hydrolyze either a fatty acid from a Meer weergeven • Kraemer FB, Shen WJ (October 2002). "Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis". Journal of Lipid Research. 43 (10): 1585–94. doi:10.1194/jlr.R200009-JLR200. PMID 12364542 Meer weergeven Web17 sep. 2024 · Lipolysis is the process by which fats are broken down in our bodies through enzymes and water, or hydrolysis. Lipolysis occurs in our adipose tissue stores, which are the fatty tissues that cushion and line … mercedes-benz 600 pullman 1963 to 1981
Hormone-Sensitive Lipase Knockouts - Nutrition
Web15 nov. 2024 · Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis. Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth. Advanced lipodystrophy reverses … WebMicroorganisms, especially those that survive in extremely cold places such as Antarctica, have gained research attention since they produce a unique feature of the protein, such as being able to withstand at extreme temperature, salinity, and pressure, that make them desired for biotechnological application. Here, we report the first hormone-sensitive … Webhormone-sensitive lipase, lipase, hormone-sensitive, monoacylglycerol lipase LIPE, retinyl ester hydrolase GeneRIFs: Gene References Into Functions Dietary fat content and … mercedes benz 600 limousine for sale