Web13 de abr. de 2024 · Infertility is a major health issue, estimated to affect ~15% of the global population ( 1 ). Human reproduction requires normal developmental processes consisting of the production of competent gametes, fertilization, preimplantation embryonic development, implantation, pregnancy, and birth. Several biological processes, including organ ... Web9 de jun. de 2024 · In mammals, translational control plays critical roles during oocyte-to-embryo transition (OET) when transcription ceases. However, the underlying regulatory …
OOCYTE/ZYGOTE/EMBRYO MATURATION ARREST 17; OZEMA17
Web10 de mar. de 2024 · Ski7, a regulator of RNA levels "When we found that Ski7 was highly expressed in the mature eggs and early embryos of zebrafish, we realized it might play … WebOzil J-P. Egg-to-embryo transition is driven by differential responses to Ca2+ oscillation number. Dev Biol 2002; 250:280-91. Generation of Oocyte-Specific Atg5-/-Mice Next, we analyzed whether this kind of autophagy is critical for early embryogenesis. Previously, we clearly showed that Atg5-/-mice die within one day after delivery,16 in-kind sponsorship meaning
From egg to embryo: How developing zebrafish keep RNA levels …
Web2 de jul. de 2024 · The Oocyte-to-Embryo Transition Is Marked by a Change in Redox State. To characterize metabolic changes at the Drosophila oocyte-to-embryo transition, we optimized a targeted metab-olomics method and compared ovaries enriched for mature oocytes (stage 14), unfertilized activated 0- to 1-h eggs, and 0- to Web29 de out. de 2009 · The molecular underpinnings of the oocyte-to-embryo transition are poorly understood. Here we show that two protein tyrosine phosphatase-like (PTPL) family proteins, EGG-4 and EGG-5, are required for key events of the oocyte-to-embryo transition in Caenorhabditis elegans. The predicted EGG-4 and EGG-5 amino acid … Web2 de out. de 2024 · We demonstrated that only the activator FZY-1, but not FZR-1, is incorporated in the APC/C complex to regulate the oocyte-to-embryo transition. Our findings suggested a genetic relationship linking the APC/C complex and OMA-1, and support a model in which the APC/C complex promotes P granule accumulation and … in-kind support and maintenance ism