Plzf transcription factor
WebOct 8, 2013 · PLZF is a member of the BTB/POZ family of transcription factors known to regulate progenitor maintenance in multiple tissues [25]. PLZF was initially identified as a protein whose functions are subverted through chromosomal rearrangements resulting in acute promyelocytic leukemia [26]. WebApr 14, 2024 · The kpc-1 gene encodes a conserved proprotein convertase KPC-1/FURIN whereas eor-1 encodes for the zinc finger transcription factor EOR-1/PLZF. Both LOF …
Plzf transcription factor
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WebMar 2, 2024 · The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 29, 391–403 (2008). Article CAS Google Scholar Lazarevic, V. et al. The gene encoding early growth ... WebJan 20, 2015 · PLZF belongs to the Broad-complex, Tramtrack and Bric-a-brac/poxvirus and zinc finger (BTB/POZ) family of transcription factors that regulate a variety of biological processes, including development, differentiation, tumorigenesis and, as is emerging, the immune response (10–13).
WebSignificance The mechanistic or mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase that integrates various environmental signals/cues to regulate cell growth, proliferation, metabolism, and survival. The WebAbstract. Little is known of the molecular mechanisms whereby spermatogonia, mitotic germ cells of the testis, self-renew and differentiate into sperm. Here we show that …
WebJul 9, 2024 · PLZF directs the acquisition of effector properties, such as the upregulation of CD44 and production of effector cytokines 19, 20. Expression of PLZF directs the acquisition of effector... Web早幼粒细胞白血病锌指蛋白（plzf）特异性表达于未分化精原细胞中，通过其锌指结构域结合dna抑制多种基因表达。plzf突变可导致进行性生殖细胞减少，最终导致精子发生障碍[14]。plzf可结合至ssc分化相关的kit基因的启动子，抑制kit基因转录及其下游基因的表达[15]。
WebJul 28, 2009 · The PLZF transcription factor is essential for the innate phenotype of NKT cells. This report shows that PLZF is likewise responsible for the innate, NKT-like …
WebJul 4, 2010 · PLZF (promyelocytic leukemia zinc finger; Zbtb16) has been identified as a key transcription factor involved in the development of NKT cells 5, 6, yet it remains unclear if and how such... biscuit and gravy egg casseroleWebApr 1, 2016 · PLZF (Promyelocytic Leukemia Zinc Finger) is a BTB-POZ transcription factor. Two co-orthologs of the human PLZF are found in teleost fish species. Zebrafish Plzf … biscuit and skip rocking horseWebJun 20, 2016 · PLZF directly binds genes encoding T-helper–specific transcription factors. Shown are PLZF ChIP-seq reads aligned at the c-Maf ( A ), Gata3 ( B ), Tbx21 ( C ), Runx3 ( … dark brown wall textureWebThe PLZF transcription factor is essential for the innate phenotype of NKT cells. This report shows that PLZF is likewise responsible for the innate, NKT-like phenotype of Vγ1+Vδ6.3/Vδ6.4+ cells. TCR cross-linking induced PLZF expression in all polyclonal immature γδthymocytes, suggesting that agonist selection might be required for PLZF ... biscuit and gravy nutritionWebNational Center for Biotechnology Information biscuit and tea hamperWebOct 8, 2013 · Here, we show that the transcription factor Promyelocytic Leukemia Zinc Finger (PLZF) plays a critical role shaping patterns of neuronal differentiation by gating … biscuit and gravy fountainWebPlzf (Promyelocytic Leukaemia Zinc-Finger) is one of the first transcription factor shown to be required for self-renewal of SSCs [ 7] and is also co-expressed along with Oct-4 in undifferentiated spermatogonia [ 13 ]. Plzf is expressed during embryogenesis and plays a crucial role during limb and axial skeletal patterning. biscuit and gravy potato chips