WebRifamycin is a clinically useful macrolide antibiotic produced by the gram positive bacterium Amycolatopsis mediterranei. This antibiotic is primarily used against Mycobacterium tuberculosis and Mycobacterium leprae, causative agents of tuberculosis and leprosy, respectively. In these bacteria, rifa … Recent trends in rifamycin research WebSSF and production of rifamycin SV using Amycolaptopsis mediterranei was observed by Nagavalli et al. (2014).The study revealed that under optimized conditions the strain could produce 20 g ...
A complex role of Amycolatopsis mediterranei GlnR in nitrogen ...
WebNov 1, 2014 · Rifamycin production and production of the diffusible yellow to orange pigment(s) in GYM agar were totally abolished in S699ΩrifN (Fig. 6 B and data not shown). This result confirms the role of rifN as an essential component of the rifamycin biochemical pathway (Floss and Yu, 2005). WebRifamycin and its synthetically modified derivatives are the principal chemotherapeutic agents used for combating tuberculosis and other mycobacterial infections (Davies et al. … gow athena
Prediction of Transcription Factors and Their Involvement in …
WebThe fermentative production of rifamycin by Amycolatopsis mediterranei (MTCC17) has been studied. Both qualitative and quantitative aspects of the fermentation were … WebApr 18, 2024 · Amycolatopsis mediterranei S699 produces rifamycin B and successors of this strain are in use for the industrial production of rifamycin B. Semisynthetic derivatives of rifamycin B are used against Mycobacterium tuberculosis that causes tuberculosis. Although the rifamycin biosynthetic gene cluster was characterized two decades ago, the … WebThe fermentative production of rifamycin by Amycolatopsis mediterranei (MTCC17) has been studied. Both qualitative and quantitative aspects of the fermentation were determined by optimizing cultural conditions and medium design to improve the production of rifamycin. A pH value of 7.0, a temperature of 26°C, an aeration rate of 250rev/min for a … gow atreus