WebThe present study investigates functional brain injury based on the relation between S100B and memory disturbances. Methods: The protein S100B was sampled during and after surgery. Explicit and implicit memory function was … WebNov 27, 2024 · S100B is a calcium-binding protein that is localized in astrocytic cytoplasm. It has been shown to be elevated systemically especially in traumatic brain injuries and strokes . Systemic levels of S100B are higher after traumatic brain injury and have been associated with poor long-term outcomes [36,37,38].
The Potential of S100 Calcium-Binding Protein B and Glial …
WebSevere traumatic brain injury ... such as S100B, glial fibrillary acidic protein, ubiquitin carboxyl-terminal hydrolase L1, myelin basic protein and neuron-specific enolase, have obtained interests of neurological researchers for helping clinical prognostic prediction and severity assessment of TBI. 9–11 However, circulating levels of those ... WebAug 1, 2024 · The best-studied biomarker is S100B, a well-established protein tumor marker commonly used for the follow-up of patients suffering from malignant melanoma [ 20 ]. In the case of TBI, S100B is elevated within 30 min after injury after release from the astroglia [ … coakley moriarty
A Literature Review of Traumatic Brain Injury Biomarkers
WebAbstract Objective We used the lateral fluid percussion injury (LFPI) model of moderate-to-severe traumatic brain injury ... Low 2d plasma levels of Thr 231-phosphorylated tau protein (pTAU-Thr 231) and S100B combined (ROC AUC=0.7790) predicted prior craniotomy surgery ... WebS100B protein is detectable at high concentrations in CSF and serum both in brain trauma and in acute brain injury caused by cardiovascular disorders, in some cases also correlating with the size of the lesion as evaluated using radiological criteria ( Persson et al. 1987; Aurell et al. 1991; Ingebrigtsen and Romner 1996, Missler et al. 1997b; … WebOct 10, 2013 · In the extensive literature on S100B as a biomarker for traumatic brain injury (TBI), no evidence appears to exist on its prognostic capacity as a predictor of BD after … coakley martha